Profil Fasilitator

Elsie S. Mainali MD., PhD, FAAP.

Section member SONPM (section member of Neonatal-Perinatal Medicine). American Board of Pediatrics, Certified in General Pediatrics and Certified in the subsection of Neonatal-Perinatal Medicine.

Link: IAOTP (International Association of Top Professionals) : https://www.youtube.com/watch?v=pjKdkBJPkvI

BOARD CERTIFICATION:

General Pediatrics Re-certified till 2027

Sub-specialty: Neonatal-Perinatal Medicine. Re-certified till 2027

EDUCATION:

08/1989 - 12/1992 Ph.D. Medical Sciences. Texas A&M University College of Medicine. College Station,TX.

07/1980 - 04/1984 M.D. Manila Central University College of Medicine. Manila Philippines.

12/1975 - 05/1979 B.S. University of the Philippines, Diliman-Quezon City. Philippines.

POSTDOCTORAL TRAINING OR SPECIAL EXPERIENCE

Internship and Residencies:

July 1992 – June 1995 Pediatric Residency Program, Department of Pediatric, Albert Einstein College of Medicine Bronx, MMC, New York

June 1984 - February1988 House Physician, Patan Hospital, United Mission to Nepal, Kathmandu - Nepal

Fellowship:

June 1995 - June1998 Neonatal - Perinatal Medicine Fellowship Program, Department of Neonatology Children's National Medical Center George Washington University, Washington DC

July 1998 – Feb 1999 Research – Fellow CNMC, Washington DC

Research Assistantship / Scholarship:

July 1989 - December 1992 Graduate Assistantship Department of Microbiology-Immunology, College of Medicine, Texas A&M University

July 1976 – December 1979 Integrated Foreign Students Scholarship. University of the Philippines

ACADEMIC APPOINTMENTS OR OTHER SIGNIFICANT WORK EXPERIENCE

August 2024-now: Locum with Kootenai Health System, Coeur D’Alene ID Level 3 NICU, through Hayes Locum

August 2023 - now: Locum with Driscoll Children through Weatherby: Level 3 NICU, Laredo Medical Center

January 2024-May 2024: Locum with Christus Mother Francis Health System, Shreveport, LA through Delta Locum Tenen: Level 3 NICU, Shreveport, LA

January 2024-May 2024: Locum with Christus Mother Francis Health System, Tyler TX through Delta Locum Tenen: Level 3 NICU, Tyler TX

May 2022 - June 20, 2023: Interim Medical Director and Chief of Neonatology, MMC-RWJBH. Monmouth, Long Branch, NJ

August 2018 - June 2023: RRT Neonatologist Mednax HQ, Sunrise, FL ( August 2018-January 2020: Harrisburg PA; January, 2020-March 2020: Saginaw, MI; January 2020 - March 2023 Orlando FL; May 2020-May 2022: Rockville and Hagerstown, MD)

April 2016 - June 2018 : Medical Director Pediatric and ICN FHS (Faquier Health System), 500 Hospital Drive, Warrenton, VA 20186

October 2015- March 2016: Interim Medical Director Nursery FHS (Faquier Health System), Warrenton VA

December 2013 - July 2016: Clinical Associate Professor VCUHS (Virginia Commonwealth University). Neonatology at CJW-VCU (Chippenham - Johnston Willis - Affiliated with Virginia Commonwealth University), Richmond, VA. Chippenham Hospital: 7101 Jahnke, Richmond VA 23225; Johnston-Willis Hospital: 1401 Johnston-Willis Drive, Richmond VA 23235

September 2013- October 2015: Neonatology consultant, Fauquier Hospital System, 500 Hospital Drive, Warrenton, VA 20186

April 1, 2013 - April 2014. Clinical Associate Professor. Department of Pediatrics. Temple University School of Medicine, Philadelphia, PA.

August 2012 - April 2014. Neonatology associate. CKHS (Crozer Keystone Health System), 1 Medical Center boulevard, Upland PA 19013.

October 2011 – October 2016. Clinical Assistant Professor, Department of Pediatrics, VCU (Virginia Commonwealth University), Richmond, VA. Inactive.

January 2010 – Jan 2012. Corporate Medical Director PDX– NICU. MWHC (Mary Washington Health System). 1001 Sam Perry Boulevard Fredericksburg, VA 22401 – 101 Hospital Center Boulevard, Stafford, VA 22401

April 2010 –Jan 2012. Medical Director – Neonatal Transport Team. MWHC (Mary Washington Health System). Fredericksburg – Stafford, VA

July 2007 – December 2009. Medical Director PDX. NICU. Sentara VBGH (Virginia Beach General Hospital). Virginia Beach, VA 23454

November 2005 – 2007. Affiliate Graduate Faculty, Graduate School. Virginia Commonwealth University. 1001 East Marshall St, Richmond, VA 23298.

March 1999 – June 2007 Assistant Professor, Department of Pediatrics, Division of Neonatal Perinatal Medicine, MCV/VCU (Medical College of Virginia/ Virginia Commonwealth University), 1001 East Marshall St, Richmond, VA 23298

November 1996 – present. Neonatal Resuscitation Program - American Academy of Pediatrics Instructor - Mentor

Gaps

March 1988 - July 1989 Preparation for graduate school

February 2012 to August 2012: Job search and processing PA Medical license

July 2018 : Job search and processing FL and MI medical license

MEMBERSHIP – SCIENTIFIC, HONORARY AND PROFESSIONAL SOCIETIES

The American Academy of Pediatrics – Fellow

The AAP section on Neonatal-Perinatal Medicine (SONPM)– Fellow

The AAP section on International Medical Graduates (SOIMG) – Fellow

CLINICAL SERVICE:

Feb 1999- May 2007 Clinical service at VCU-HS NICU: 36 beds of level 3C (with all surgical services and ECMO facility: one of the 2 ECMO services in the State of Virginia; Supervising 5 NNPs and three neonatology-fellows, plus pediatric –residents in training).

June 2007- December 2010: Medical Director of a 12 beds of level IIIb NICU at Sentara Virginia Beach General Hospital, Virginia Beach, VA. Jan 2011-Jan 2012: Corporate Medical Director, a 17 beds of level IIIb NICU and 6 beds of level IIa ILN at MWHC, Fredericksburg, VA April 2011-Jan 2012: Medical Director, Neonatal Transport Team MWHC, Fredericksburg, VA

August 2012 - April 2014: neonatology associate CKHS group, Upland PA (level 3B facility).

September 2013 - March 2016: clinical contractor FH, Warrenton, VA.

November 2013 - October 2017: neonatology clinician, Richmond, VA

October 2016 - July 2018: Medical Director FHS Warrenton, VA

August 2018 - June 2023: Neonatologist, member of Regional Rapid Response Team, Mednax HQ. Regional assignments in Mednax units: Harrisburg PA (level 3), Saginaw MI (level 3), Orlando FL (level 4), Rockville MD (level 3), Hagerstown MD (level 2), Cumberland MD (level 2). June 2023 - Now: Locum neonatologist at level 3

CONTINUING QUALITY IMPROVEMENT PROJECTS

• Co-founder and co-owner of Blog and Podcast “Neonatali” . https://neonatali.com/ December 2024 till now

• “Synchronization of Practice in respiratory care management in SCN” Meritus Medical Center, Hagerstown. February 2022 till 2023

• “To Reduce LOS and Increase mother-baby bonding in NAS in 5 counties surrounding Fauquier” September 2014 - 2018

• Decreasing readmission of jaundiced babies at FH. June 2014 till June 2016. Submitted and received credit from ABP • Improving NEC rate in CKHS NICU. 2013-2014

• Improving the incidence of “Unplanned Extubation Rate” in CKHS NICU. Nov 2012

• Parents satisfaction survey. Leader. Jan 2010 till Jan 2012

• Physicians relational coordination. Leader Jan 2010 till Jan 2012.

• Enhancing breastfeeding in the community and in the NICU. Co-Leader. Jan 2010 till Jan 2012 • Elimination of medication errors. Co-Leader. Jan 2010 till Jan 2012.

• QI: Improving BPD rate in ELGAN babies, based on Jensen classification, Accredited and received points from ABP (November 2022)

COMMUNITY WORK:

2001 – Clinical and Research mentor for the summer Governor’s Program

2006 – Career motivation talk: “Prematurity and Humanity”: Governor School.

2008 – Organizer of Annual Symposium on Community Neonatology at Virginia Beach. 2009 – Member of Virginia Beach Early Learning Policy Board

2009 – Member of Virginia Beach Fetal Infant Mortality Review Program – Community Action Team

2010 – June 15: Organizer: Community Outreach Program: UMW Alumni center: MOC: Dr. Brown VP, ABP (Main-speaker). Community introduction to our group Breastfeeding Initiative Project.

2010 – 2012: Member of Steering Committee, Virginia Neonatal Practice Collaborative Committee.

2010 –2012: Member, Board of Director: Healthy Families America. Rappahanock chapter

2016 - 2018: Building Coalition to care for opioid user mom-baby perinatally in Fauquier county and surrounding

MAJOR COMMITTEES:

2002-2003 Member, VCU Institutional Review Board

2009 Member Sentara Virginia Beach Quality Improvement Committee

2009 Member Sentara Virginia Beach OB Patient Safety Committee

2010 Member MWHC Patients Safety Action Committee

2011 Member MWHC Pharmacy and Therapeutics Committee

OTHER SIGNIFICANT SCHOLARLY, RESEARCH OR ADMINISTRATIVE EXPERIENCE

September 2023 - February 2024. Leading Organization to Health Program. AAMC

2007- 2010: Reviewer: Pediatrics. The official journal of the American Academy of Pediatrics.

February 2007: Faculty – VCU Honors Summer Undergraduate Research Program.

Summer 2007. “Biomarkers of inflammatory cells in periventricular hemorrhage - leukomalacia in the brain of premature infants”. January 2007: Advisor: Stem Cell Institute and Cancer Institute, Indonesia. Jl. Jend. A. Yani No.2, Pulo Mas. Jakarta 13210, Indonesia.

November 2006: Reviewer: Medical Science Monitor. International Scientific Literature, Inc. Albertson, NY 11507

March 2006: Reviewer. Cellular of Immunology. Elsevier. San Diego, CA 92101-4495

February 2006 - present: Designed course for: Certificate in basic management of NICU for International Neonatologists. Department of Pediatrics, Virginia Commonwealth University, Richmond, VA 23298

June 2005 - 2007. Grant Reviewer. Australian Stem Cell Center Ltd. Monash University, Wellington Road, Clayton, Victoria, 3800.

2002 - 2005. Co-Chair. Continuing Medical Education in Neonatology - Harapan Kita Hospital – Department of Pediatrics, University of Indonesia, Jakarta - Indonesia.

SPECIAL AWARDS, FELLOWSHIPS AND OTHER HONORS

1998-2000. AAP Prep Education Award

2009- Certification on Medical Leadership Program – MEDNAX (PDX)

2013 - Certificate of completion. “ Lean Tool Box for continuous Improvement part I and II. Crozer Chester Medical Center, Upland PA

BIBLIOGRAPHY

Mainali, E.S, Green C, Rozycki, H and Gutcher G. 2007. The safety and efficacy of high frequency jet ventilation with nitric oxide in neonatal transport. J Perinatology Oct;27(10):609-13. Epub 2007 Aug 16.

Masalunga C, Rozycki H.J and Mainali E.S. 2007. The impact of hyperoxia on the developing dendritic cell: neonatal versus adult. Pediatric Research 62: 1-2.

Masalunga C, Cruz M, Porter B, Chui B, Roseff S and Mainali E. S. 2007. Increased hemolysis from saline pre-washing RBCs or centrifugal pumps in neonatal ECMO. J Perinatol Jun; 27(6):380-4; [Epub 2007 Apr 19]

Hitoshi Minamiguchi, John R. Wingard, Joseph H. Laver, Elsie S. Mainali, Leonard D. Shultz, Makio Ogawa. 2005. NOD-Rag1nullPrf1null mice support long-term engraftment of human hematopoietic stem cells. Biology of Blood and Marrow Transplantation: Jul;11(7):487-94

Mainali, E.S.; Kikuchi, T., and Tew, J.G. 2005. Dexamethasone inhibits maturation and alters function of monocyte-derived dendritic cells from cord blood. Pediatric Research. Jul;58(1):125-31; [Epub 2005 Mar 17].

Mainali, E.S. and Tew, J.G. 2004. Dexamethasone selectively inhibits differentiation of cord blood stem cell-derived dendritic cells precursors into immature dendritic cells. Cellular Immunology: Nov-Dec; 232(1-2):127-36. Epub 2005 Apr 26.

Yoonkyung Do - Elsie Mainali, Prakash S. Nagarkatti and Mitzi Nagarkatti. 2004. Bryostatin-1 in combination with calcium ionophore promotes the maturation of human umbilical cord blood monocyte-derived dendritic cells capable of activating neonatal alloreactive T cells. Cellular Immunology: Sept-Oct; 231(1-2):8-13. Epub 2004 Dec19.

Mainali, E. S. and McMurray, D. N. 1998. Protein deficiency induces alterations in the distribution of T cell subsets in experimental pulmonary tuberculosis. Infect. Immun. Mar; 66(3): 927- 931

Mainali E. S. and McMurray, D. N. 1998. Adoptive transfer of resistance to pulmonary tuberculosis in guinea pigs is altered by protein deficiency. Nut Research Feb18(2): 309-317

McMurray, D. N., Mainali E. S. and Phalen, S. 1993. Malnutrition, Immunoregulatory defects and the white plague. Adv. Biosci. 86: 19 - 28.

Hill, K.W and Mainali E.S. March 14-16, 2018. Fauquier Community Coalition of Family Centered Neonatal Abstinence Syndrome Care. National Perinatal Association Annual Conference. Loma Linda, CA

Nandita Patnaik, Hanlon, A , Mainali, E. 2014. Five Year Study on Maternal-Infant Predictors of Necrotizing Enterocolitis in an Urban Community NICU. Pediatric Research Society. Vancouver, Canada. Poster symposium. Abstract # 715521.

Anthony Suchman, Jody Hoffer Gittell, Elsie Mainali. Using the Relational Coordination survey instrument to improve workplace culture. Workshop at “American Academy in Communication in Health care. October 16-19, 2011 Chicago USA.

Mainali, E.S., Tew, J.G. and Walsh, S.W. 2007. Mature DC and NK cells are elevated in the placenta of premature infants. Pediatric Research Society. Toronto, OT-Canada. Poster symposium. Abstract #752796.

Varandani, A., Walsh, S.W., and Mainali E.S. 2007. The abundance of activated neutrophils and scarcity of anti-inflammatory cytokines in the placenta of premature infants. Pediatric Research Society. Toronto, OT-Canada. Poster symposium. Abstract #751769

Mainali, E. S. and Tew, J.G. 2006. Influence of corticosteroid on E. coli induced neonatal dendritic cell maturation. The Journal of Immunology. Program Issue AAI. 55.21: S87

Mainali, E. S. 2003. The role of protein kinase C in enhancing the maturation and function of dendritic cells derived from adherent cord blood monocytes. Pediatric Research Program Issue APS-SPR. 53(4 part 2): 374A

Mainali, E. S. 2003. Potentiation of antigen presentation by stem cell-derived dendritic cells to neonatal autologous T cells. Pediatric Research Program Issue APS-SPR. 53(4Part 2): 374 A

Mainali, E.S., Do, Y., Nagarkatti, P and Nagarkatti, M. 2002. Strategies for enhancing function of human cord blood dendritic cells. Pediatric Research Program Issue APS-SPR 51(4 part 2): 309A-310A.

Mainali, E.S.,and Thomas F. Huff. 2001. The Role of TGF-β on telomerase activity on human mast cell leukemia (HMC-1). Pediatric Research Program Issue APS-SPR. 49(4 part 2): 12A

Mainali, E.S., Taylor, B., William Merritt. 1999. In-vitro enhancement of immuno-phenotypic and functional activation of human cord blood T naïve cells with tetanus toxoid. Pediatric Research Program Issue APS-SPR. 45(4) Part 2 of 2:263A

Mainali, E.S.,Hsiao, D., and Barbara Taylor. 1998. Restriction of proliferation of cord blood T lymphocytes by blocking the antigen presentation with monoclonal antibodies against MHC molecules, CD4 or CD8 epitopes. Pediatric Research Program Issue APS-SPR. 43(4) Supplement 2: 240A.

Mainali, E.S., Taylor, B., Hsiao, D., Revenis,M., Rais-Bahrami, K., Short, B.L., and Naomi Luban. 1998. Immunological profile after multiple blood and blood products transfusion in neonatal ECMO. Pediatric Research Program Issue APS-SPR. 43(4) Supplement 2: 240A

Mainali, E. S. and McMurray, D. N. 1992. Influence of infection route in the generation of immune lymphocytes by guinea pigs infected with virulent Mycobacterium tuberculosis. FASEB J. 6: A 1335

DISSERTATION

Mainali, E. S. 1992. Function and distribution of Thymus dependent lymphocyte subsets involved in resistance to experimental pulmonary tuberculosis. Unpublished doctoral dissertation, Texas A & M University Health Science Center, College Station, TX. 16.

PRESENTATION

Organizer and Speaker Seminar on “Addressing the Opioid Crisis: Treatment that Works”. October 11, 2017. Fauquier Health System. Warrenton VA.

Speaker at “Virginia Neonatal Practice Collaborative” “IMR/NMR” what we can do to improve? May 11, 2011

Speaker at “Rescue Round Schedule”. EMS – Virginia Beach. “OB and neonate emergencies”. August 12, 2009.

Speaker at Tidewater Association of Neonatal Nurses, on “Delivery Room 911” at quarterly meeting. Virginia Beach. June 3, 2009

Speaker at Preconceptional and Interconceptional Health Promotion on “Newly Revised AAP/ AHA Guidelines for Neonatal Resuscitation”. Mead-Johnson and the Virginia Department of Health, Division of Women’s and Infant’s Health, Maternal Child Health Services. Richmond, VA. May 31, 2006.

International Faculty in “the Principles of Basic Neonatal Care” Training Course. February 11 – 27, 2006, Bandung-Surabaya, Indonesia. USAID public health project

Organizer and initiator of “Prematurity and Humanity” through Women Health Institute, Virginia Commonwealth University. Feb 8, 2006

Course organizer and Speaker of the Third Indonesian Neonatal-Perinatal Seminar and Workshop. July 11-17,2005. Jakarta, Indonesia.

Course organizer and Speaker of the Second Indonesian Neonatal-Perinatal Seminar and Workshop. October 21-31, 2002. Jakarta, Indonesia.

Speaker. Continuing Medical Education. Lecture series. Respiratory Distress in the Newborn. October 2nd, 2001. Mary Washington Hospital, Fredericksburg, VA.

Pediatric Research Forum. The role of TGF-β on telomerase activity in human mast cells. March 2000. Department of Pediatrics. Medical College of Virginia / Virginia Commonwealth University. Richmond, VA.

Pediatric Grand Round. Neonatal Immunology. February 2000. Medical College of Virginia / Virginia Commonwealth University. Richmond, VA.

CONSULTANCY

Neonatology Consultant to Faquier Hospital, Warrenton, VA September 2013 Till October 2015

International consultancy to USAID public Health Project, the Indonesia Health Services Program: decreasing Neonatal Mortality Rate in Indonesia. 2005-2009.

RESEARCH/QI PROJECT QI (PI)

Improving Outcome by Synchronization of Respiratory Management in the community NICU. 2021- now. Meritus Medical Center. Hagerstown, MD

QI (PI) To improve the outcome of Neonatal Abstinence Syndrome through a community effort. 2018. Family Birthing Center Fauquier Hospital. Accredited by ABP MOC 4 activities.

QI (PI) Reducing the rate of readmission for jaundice newborns. 2017. Faquier Hospital, Warrenton, VA. Collaboration effort Neonatology and Community Pediatrician. Accredited by ABP MOC 4 activities

Periodontitis, prematurity and Neonatal Outcome. PI in grant proposal submitted to Interschool A.D. Williams R & D 2007. Funded for $ 75,000

The role of dendritic cells in human neonate (Funded by A.D.Williams R&D 2002-2003). $ 15,000.00

In vitro immunization of human cord blood progenitor T cells (Funded by A.D. Williams R&D 2001-2002). $10,000.00

The Indonesian Neonatal-Perinatal Seminar and Workshop. Head of Curriculum Committee and Chief Organizer/Speaker. 2002 and 2005.

The role of TGF-β on telomerase activity in human mast cell –1 (Funded by American Cancer Society, 1999-2000). $12,000.00

SUPERVISOR to Neonatology-fellows, medical and graduate students (research project)

“Comparative study of Bilirubin Management: Conservative versus Aggressive” 2022. Trainee: Marina Domatova D.O. (FP resident. MMC Hagerstown MD)

“Strong Predictors of NEC in our community” 2013. Trainee: Nandita Patnaik M.D. (Pediatric Resident, CCMC)

“Role of dendritic cells in the pathogenesis of bronchopulmonary dysplasia”. 2006. Trainee: Stephanie Smith M.D. (Neonatology-Fellow)

“Early markers of periventricular leukomalacia as predictors of neurodevelopmental outcomes”. 2006. Trainee: Anjali Varandani M.D (Neonatology – Fellow).

“Bio-development of osteocytes derived from mesenchymal stem cells of cord blood and adult bone marrow”. Graduate student (M.S. Physiology-Biomedical Engineering): Andrew Pacitti (Graduated – 2006).

“The effect of hyperoxia on the development of neonatal dendritic cells” (2003-2004).Trainee: Cynthia D. Masalunga M.D (Neonatology – fellow).

“The effect of washed blood on the integrity of erythrocyte’s membrane” (2003-2004).Trainee: Mercedes A. Cruz M.D (Neonatology – fellow).

PRECEPTOR/MENTOR to residents and medical students

Family Practice Medicine Resident: Marina Domatova (2022 till 2023)

Pediatric resident: Nandita Patnaik ( 2013 till 2014)

Pediatric residents: Stephanie Smith (2003-2006; fellow Neonatology); Peggy Chang (2003-2006; fellow Hematology-Oncology); Janet West (2003-2006; General Practice) Medical students: Candice Greene (2004-2005); Allison Lange (2007).

LANGUAGES

English (proficient in written, reading and spoken language)

Bahasa Indonesia (native tongue: proficient in written, reading and spoken language)

Tagalog (proficient in written and spoken language)

Nepalese (proficient in spoken language)